Synthesis and in vitro cytotoxicity evaluation of 4-aminoquinoline derivatives
نویسندگان
چکیده
منابع مشابه
2-(4-Fluorophenyl)-N-phenylacetamide Derivatives as Anticancer Agents: Synthesis and In-vitro Cytotoxicity Evaluation
Cancer is a major global problem and is the second leading cause of mortality in the developed countries.Resistance to current chemotherapeutics and high incidence of adverse effects are the two principal reasons for developing new anticancer agents. Phenylacetamide derivatives can act as potential anticancer agents. Synthesis and screening of 2-(4-Fluorophenyl)-N-phenylacetamide derivatives in...
متن کامل2-(4-Fluorophenyl)-N-phenylacetamide Derivatives as Anticancer Agents: Synthesis and In-vitro Cytotoxicity Evaluation
Cancer is a major global problem and is the second leading cause of mortality in the developed countries.Resistance to current chemotherapeutics and high incidence of adverse effects are the two principal reasons for developing new anticancer agents. Phenylacetamide derivatives can act as potential anticancer agents. Synthesis and screening of 2-(4-Fluorophenyl)-N-phenylacetamide derivatives in...
متن کامل2-(4-fluorophenyl)-n-phenylacetamide derivatives as anticancer agents: synthesis and in-vitro cytotoxicity evaluation
cancer is a major global problem and is the second leading cause of mortality in the developed countries.resistance to current chemotherapeutics and high incidence of adverse effects are the two principal reasons for developing new anticancer agents. phenylacetamide derivatives can act as potential anticancer agents. synthesis and screening of 2-(4-fluorophenyl)-n-phenylacetamide derivatives in...
متن کامل2-(4-Fluorophenyl)-N-phenylacetamide Derivatives as Anticancer Agents: Synthesis and In-vitro Cytotoxicity Evaluation
Cancer is a major global problem and is the second leading cause of mortality in the developed countries.Resistance to current chemotherapeutics and high incidence of adverse effects are the two principal reasons for developing new anticancer agents. Phenylacetamide derivatives can act as potential anticancer agents. Synthesis and screening of 2-(4-Fluorophenyl)- N-phenylacetamide derivatives i...
متن کاملDesign, Synthesis, SAR, Docking and antibacterial evaluation: Aliphatic amide bridged 4-aminoquinoline clubbed 1,2,4- triazole derivatives
A series (7a-7k) of aliphatic amide bridged 4-aminoquinoline clubbed 1,2,4triazole derivatives were designed on the basis of field alignment and mapping and finally synthesized via six step synthesis protocol. The antibacterial activities of all the synthesized molecules were performed on different gram positive and gram negative bacterial strains. Compound 7a, 7d and 7h were found most active ...
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ژورنال
عنوان ژورنال: Biomedicine & Pharmacotherapy
سال: 2008
ISSN: 0753-3322
DOI: 10.1016/j.biopha.2007.04.007